Shortest distance is straight to northern tip of Guana Island, then turn left. Add 0.4nm to go to northern tip of Great Camanoe then pass south of Guana Island at Monkey Pt. Add 2.0nm to pass between Great Camanoe and Scrub Island then pass south of Guana Island.

Unless you want to sightsee, I would take the direct route. The difference in course heading from Anegada between these options is insignificant.

Note that the White Bay, Guana Island anchorage is exposed to north swell that wraps around the headland. It can also get lumpy when the wind is up from E to SE and it accelerates around the hillsides.