Hi Diane... I don't think driving in Malta is particularly difficult. They drive on the correct side ( duel) of the road. But seriously, I swap between driving on the left and the right every couple of months. It will seem weird at first but I never find I have to think about for more than the first few minutes. My only recommendation would be to make sure you rent an automatic. Changing gear in a manual using the wrong hand really does take some getting used to. Stick to an automatic and you'll be fine. cheers