We have chartered from St. Vincent numerous times and are booked with Barefoot for 10 days in June. If you are considering them, I would recommend one of their newer boats. Horizon also has a small fleet of older boats from St. Vincent as well. It used to be an adventure to get to St. Vincent via Barbados and then direct on Liat (need I say more), or with SVG Air with pit stops in Union, Canouan, and Bequia before you get to St. Vincent. With the new airport, AA now has non-stops from MIA to AIA.

My preference is to start/stop from St. Vincent or do a one way and drop the boat in Grenada. The advantage I see in starting from St. Lucia is a stop at the Pitons. There is not much else on the west coast of St. Vincent besides Keartons and the Rock Side Cafe I'd recommend.