LastMango and I chartered out of SXM last August. We loved it. Secluded anchorages if you want. Busy anchorages if you want. We took in St. Martin, Anguilla, St. Barts and Saba. Quite a bit of open water sailing, but that was a big part of the draw for us. The only downside with our itinerary was check in/check out at each island. Not complicated, just a required nuisance and something to consider. Provisioning was easy.

http://www.wolfbaywatch.org/