My crew and I have done this multiple ways. Plow directly from JVD to Anegada or, follow the lee side of Tortola and cut between Guana and Great Camanoe Islands with mixed results. It's really all about the weather and the prevailing swells and wind chop.

A power cat certainly handles either route quite well, it's a matter of how the crew handles it should there be larger swells. We've also been blessed with a trip that was as smooth as an inland lake.