There are obviously some differences but they're easily learned, particularly by an experienced sailor who will undoubtedly have a list of good questions for the briefer. If you're still uncertain, do what I did and hire a skipper for the first day or so. Having someone to watch over my shoulder for my first time mooring, anchoring, docking, reefing, etc. was a great way to gain a lot of knowledge in a short time.
And trust me, the difference in room is worth it! The only time we cruise on monohulls now is if a cat is not available in the area.
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