I was there last week, in a Dufour 35 from Dream Yacht Charters in Fajardo. Spectacular sailing trip. Here are a few highlights:

1. Sailing was easy. Mostly line of sight, reefs well charted and marked, anchorages easy to enter, nothing tricky or surprising.
2. Didn't need water, so I can't comment on that.
3. Anchored every night except for one on a mooring in Esperanza--could have easily anchored there too.
4. Mooring balls on Culebra are free, the ones in Esperanza, Vieques are private and cost $25. The guy will come by to collect. Some of the mooring balls on Culebra are marked 'Day Use Only' but Cap'n Suzy from DYC says its OK to overnight on them.
5. Took a day mooring on the west side of Culebrita and hiked up to the lighthouse. Trail isn't marked from the beach, but if you walk south along the beach you'll see a big opening in the mangroves--that's the trail. Pretty easy to find. Swarms of white butterflies surrounded us as we hiked up the hill. Lots of goats up there and lots of goat by-products, but light house ruins were pretty cool and the views very nice.
6. Locals were all incredibly friendly and gracious.
7. We did the 2130 bio-bay tour through FunBrothers in Esperanza--incredible and worth every penny of the $55. There were 5 people in 3 kayaks + the guide and we were the only ones in the bay. Guide was knowledgable and good. Def recommend the late tour so you get the darkness after the moon sets.
8. We anchored one night in Puerto Ferro, Vieques. Some mild luminescence there, but nothing like the bio bay tour. Water in Puerto Ferro was kind of green and murky, but the bay was quite and peaceful--we were the only boat except for a handful of abandoned boats anchored near the north edge of the bay. Shallow entrance, we saw a low of 7.2 feet entering, but the depths seem accurately charted.
9. Dinner at El Quenepo in Esperanza, Vieques was superb. Superb food, superb service, superb presentation, very nice ambience. I travel all over the word and eat at lots of fancy restaurants, and this one is right in the league with the best of them. A little pricier and fancier than the rest, but truly a great dining experience.
10. Didn't buy a whole lot of provisioning during the trip but saw a grocery near the Dinghy Dock in Culebra. The Green Store in Esperanza has great google reviews, but stank like a dead rat (literally) when we were there, and the meat freezer was broken with all the meat rotting inside. We left with and onion and a can of black beans.
11. Anchoring off Punta Arenas, Vieques was spectacular. Still no road access to the beach since the hurricane, so we had the beach to ourselves. One other boat anchored in the area. Slight rolls from a south swell, but a beautiful night.