I don't know about the bus part of it, but Miami and FLL are the only nonstops from Florida, certainly. AA from Miami and Jet Blue and Spirit from FLL, although with the prices on the other two right now, no reason to ME to take Spirit. We generally drive 3.5 hours one way to Miami or 3 hours to FLL from Central Florida. If you're willing to do a connection, you can get to Tampa or Orlando quicker than getting to Miami and do a connection through Atlanta on Delta. It's been my experience that the connections on AA from Central Florida are timed really stupidly, to connect to SXM, so not much reason to connect on AA from Central Florida. Someone here once suggested doing a one way car rental, but it seems like a lot of trouble. There is a train, I believe, but I have no idea how long it would take on the train, and I think the train makes several stops?