My wife and 2 of my daughters have all had 2 shots of the Pfizer vaccine. None had any issues after the 1st shot. My 2 daughters both did not feel good during the night after the 2nd shot (chills, headache, etc.). Both went to work the next day. Although it was not great, both said it was nothing that would deter them from getting the shot again. My wife had no issues after the 2nd shot.