Can only share my experience but hope it helps. We skipped the pcr test because no one could guarantee timely results. We were leaving on a Tuesday so had to schedule our antigen test on a Sunday morning--which fortunately for us was not an issue. Keep in mind this was Easter Sunday. I submitted my form at 11:15 a.m. that Sunday morning and was approved 45 minutes later. Submitted the wife's 15 minutes after mine and 6 hours later she was denied. You can go back and look at my post of April 5 or so which fully explains but long story short, I determined she was denied because the test report did not include the specific name of the antigen test used (despite my being approved with the same test info). I got the lab to add the name of the test used, resubmitted at about 7:00 p.m. (again on Easter Sunday) and she was approved within 2 hours. So my advice based on my experience--skip the pcr test, get your antigen test at 11:30 a.m. or shortly thereafter on Saturday morning and MAKE SURE that all required info is included on that test report--especially the specific antigen test used. There are many many FDA approved for emergency use antigen tests so it would be hard to get an antigen test that is not approved but you can ask to make sure. EHAS site says approval can take up to 12 hours but even on Easter Sunday, we got fairly quick responses. In your case, even if it took 12 hours (which is not likely), you should be fine. Ultimately, do what you are comfortable with but if you make sure your lab reports have complete info, and you are careful when you fill out required forms, you should be fine. Couple of other things--make sure you have your test reports in pdf files as some have said jpg files aren't accepted. Also, use separate emails for you and your wife as some have said this was an issue (I even used separate credit cards for payment just to be safe). Do these things and you should get your approvals in plenty of time.