I have had mixed success with AMEX cards in the BVI. I don't recall ever using AMEX to rent a car in Tortola except with the major chains at the airport. Typically I use Jerry and he does not take AMEX but he takes my VISA every time. Dean in Anegada doesn't accept AMEX but other cards are OK. Don't remember what I have charged in Virgin Gorda, but some kind of card is OK. Still, I never travel without AMEX. The airlines take it for tickets and in-flight charges and whatever else. Native Son ferry uses AMEX for the boat ride. Pusser's West End, Sugar Mill, and Rhymer's in CGB all accept AMEX. Bobby's Market accepts VISA but not AMEX, same for Red Rock restaurant and Bananakeet, just off the top of my head. Most merchants I know hate AMEX.