I bought Retin A last summer at the Phillipsburg Pharmacy and the Cole Bay Pharmacy and it was 21.00 for the large tubes. I bought the strongest they had which is the .1%. I didn't need a prescription for it. You can buy as many as you want. I needed a Z-Pack for a sinus infection, but I didn't have a prescription . Not a problem the pharmacist said. She called the Dr.,and I paid her 25.00 for the Dr,'s call + the cost of the z pack. They were very helpful with all our needs.