We booked our flights yesterday. Will be in Rome from May 16-19, then on to the Tuscan Women Cook culinary program for a week. We'll have a day on the other end of the trip where we'll either come back to Rome or stay in Florence before returning to the airport for our flight home.

Not having been to Italy, any suggestions for things to do and see in the short time we have in Rome would be greatly appreciated!

I'm thinking the Coliseum is a must, and the Vatican (mostly for the Sistine Chapel). What else?