Thanks for the advice everyone.
FLJim: We will bring a boat load of bug spray!
Matt W: We have used your website a lot, thanks for that resource and your comments. Our first stop after Fajardo is planned to be Punta Arenas.
BaardJ: We plan now to take a tour of Mosquito Bay and give Puerto Ferro a miss.
TomGarvey: We will adjust our plans for Culebra to include Bahia de Sardinas (we plan to spend 3 of the 7 nights around Culebra).
As usual when sailing, everything will be a game day decision. This is our first visit and we are looking forward to a new experience after several visits to USVI/BVI.
Thanks again