I have picked up moorings truly singlehanded many times. With two people it simply not difficult. The secret is have everything ready in advance and make it a two step process. Have the person picking up the mooring simply tie the mooring line directly to the boat. After that you sort out the bridal, release the mooring line and your all set. It's when you try and do it all at once things go south. Control the line first, then rig the bridal.
G